“We got in kind of late today, and everybody jumped off the bus, except me… I had to change my clothes… and I looked out the window, and there was a man in his underpants… directly across from the bus… and was just sort of walking around like, ‘it’s cold’. And I felt like I was finally at home. Which brings us to this next song, ladies and gentlemen, which is called ‘We Live In A Dump’.” Preface to one of their uniquely They Might Be Giants songs, by one of the two founding members, John Flansburg, painting an accurate picture of the immediate area surrounding The Warfield in San Francisco in a uniquely perceptive and humorous TMBG way. The Grammy Award-winning duo and backing band have long been pioneers in alternative and experimental music, breaking into the mainstream with their third studio album, Flood (1990), which included hits “Birdhouse in Your Soul” and “Istanbul (Not Constantinople)” and well known for their “Boss of Me” theme song to the television series, Malcolm in the Middle. Last night’s show included a great mix of old and new material, including songs from their 16th studio album, Nanobots, released just a few months ago. The packed theater seemed to be filled with hardcore fans, which wasn’t surprising given that their work is so unique and they have been so prolific over more than a quarter century that they’ve cultivated quite a following.